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Research Assistant

The Walter and Eliza Hall Institute of Medical Research - Melbourne, VIC

Biotech, R&D, Science
Source: uWorkin


Full Job Description
An opportunity is available for a Research Assistant to join the Pellegrini Lab, and to participate and oversee research in infectious disease pathogenesis and therapeutic development pipelines at Australia’s pre-eminent biomedical research institute.

About the position

An excellent opportunity exists for a Research Assistant to join the Pellegrini team of the Infectious Disease and Immune Defence Division, to participate in cutting-edge research into host/pathogen interactions, disease pathogenesis, and therapeutic interventions. The Research Assistant will enjoy a high degree of operational responsibility.

Key responsibilities

Responsibilities include, but are not limited to:
Development and characterisation of mouse models of infection (HIV, HTLV-1, LCMV, HBV, SARS-CoV-2, Mtb) under the leadership of a senior member of staff.
Leading in expertise on behalf of the Laboratory for a subset of technologies, including human immune system (HIS) mouse production and other highly technical mouse procedures and surgeries.
Acquiring and maintaining a high level of expertise in relevant technologies and procedures, in order to train and advise other lab members and visiting collaborators.
Routine processing of RG2 and RG3 infectious samples, including viral quantification (TCID50 assays), RNA purification and qPCR, and production of stocks
Shared aspects of PC3 lab management, such as ordering, restocking items, equipment maintenance/testing, other compliance-related tasks
Operation of Laboratory record-keeping systems, including Electronic Lab Notebooks (LabArchives), Animal Management System (AMS),and WEHI intranet (Sharepoint, Teams, etc)
Management of samples and data using standard tools available in the Laboratory, to an exceptional standard
Participation in educational programs to disseminate technical information and train users
Supervisory and safety responsibilities in the absence of senior staff
Maintaining positive relationships with the various internal and external teams across projects
Selection Criteria
Dip Applied Sci, BSc or equivalent
Essential knowledge and practical expertise working in a PC3 Laboratory environment, including handling animals infected with RG3 pathogens and performing high-risk procedures safely and effectively
Demonstrated ability to operate with a “safety first” mindset, which includes constant attention to risk assessment and risk reduction
Essential technical expertise and experience as a Trainer with high level mouse procedures, including:
General husbandry (maintenance of colonies, mouse identification, DNA sampling)
Identification of disease (visual and palpation)
Injections (intra-peritoneal, sub-cutaneous, intra-venous, intra-facial, intra- muscular, intra-dermal, intra-splenic, retro-orbital)
Post-mortem organ collection (various)
Anaesthesia (injectable and inhalant)
Blood collection (retro-orbital, mandible, tail, cardiac puncture)
Surgical procedures
Essential experience generating Human Immune System (HIS) mice
Desired interest in infectious disease technologies and applications, including introducing new techniques and technologies, maintaining and running existing in vitro and in vivo models and providing troubleshooting and expert practical advice.
The demonstrated ability to work across multiple parallel projects or technologies in roles including sample processing, project / workflow co-ordination, and providing training and advice.
Clearly demonstrable ability to complete a variety of routine tasks efficiently and to a high standard.
Terms of appointment

This position is available for 1 year in a full time capacity. Salary is HEW 6 ($82,321 - $89,108). Up to 17% superannuation and very attractive salary packaging options are available.

General enquiries can be directed to Marc Pellegrini - pellegrini@wehi.edu.au

A position description is available here.

How to apply

Please email your application including cover letter, CV and a letter addressing the key selection criteria in pdf format to jobapplications@wehi.edu.au, quoting reference WEHI/LPMPRA230421 in the subject line.

Application closing date: 7 May 2021

Institute Life

At the Walter and Eliza Hall Institute we strive to ensure our staff and students enjoy a great working environment. We value diversity and gender equity in our work force and promote flexible working arrangements for staff to balance working requirements and personal needs. We have implemented a number of gender equity initiatives to support women laboratory heads.